Understanding & Controlling Aggression | Huberman Lab Podcast #71

This episode I describe the neural mechanisms that activate and control aggressive states and behaviors and the role of hormones–estrogen and testosterone–in mediating violent and/or competitive aggression. I will also discuss tools that can be used in order to control the factors that are known to trigger aggression. These include sunlight, estrogen sensitivity and competition within social settings. I will discuss the effects of caffeine and alcohol on impulsive behavior and how nutrition and supplementation can be used for mood regulation and aggression.

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Article Links
Photoperiod reverses estrogens’ effects on male aggression through genomic and nongenomic pathways. Z
Testosterone, occupational choice: Actors, Ministers and Other Men: S
Age, Testosterone, Behavior, and Behavior among Female Prison Inmates: t
Testosterone Rapidly Boosts Threat Reactivity in Healthy Men: A Novel Two Step Pharmacological Challenge Paradigm Q
Self-regulation and indirect aggression in the context of caffeinated and noncaffeinated alcohol consumption: 3
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The effectiveness of carnitine for children with attention deficit hyperactivity disorder (ADHD):Functional identification of an aggressive locus in the mouse hypothalamus. (See “Supplementary Information” for movies): B

Book Links
An Introduction to Behavioral Endocrinology 5th edition: 9
The Nature of the Beast: How Emotions Lead Us: 3

Other Links
When VMH stimulation is applied, mice switch from mating behavior towards aggressive behaviors:VMH stimulation causes mice to exhibit aggressive behavior towards inanimate objects (e.g. gloves):
Timestamps
00: 00: 00 Aggression, Types of Aggression
00: 03: 33 AG1 (Athletic Greens), ROKA, Helix Sleep
00: 08: 29 Neural Circuits for Aggression, “Hydraulic Pressure Model”
00: 15: 50 Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH)
00: 22: 14 Psychiatric Disorders & Aggression
00: 23: 36 Stimulation of the VMH, Estrogen Receptors & Aggression
00: 31: 57 Neural Circuits Mediating Physical Acts of Aggression, Biting
00: 35: 56 Testosterone & Competitiveness/Estrogen & Aggression
00: 43: 00 Sunlight, Melatonin & Aggression
00: 45: 46 Cortisol, Serotonin & Aggressive Behaviors
00: 51: 56 Tool: Omega-3 Supplementation & Mood
00: 54: 18 Tool: Sunlight, Sauna & Cortisol Reduction
00: 55: 54 Tool: Ashwagandha & Cortisol Reduction
00: 57: 06 Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity
01: 00: 37 Testosterone & Aggression, Competitive Work Environments
01: 05: 07 Testosterone, Amygdala, Challenge & Effort
01: 09: 27 Caffeine, Alcohol & Impulsivity
01: 13: 15 Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression
01: 17: 18 Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior
01: 24: 10 Factors Affecting the “Hydraulic Pressure Model” of Aggression
01: 25: 44 Book by Dr. David Anderson, Aggression & Social Relationships
01: 27: 35 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter

The HubermanLab Podcast is intended for informational purposes only. It does not represent the practice of medicine or nursing, nor the giving of advice. No doctor/patient relationship is established. You are responsible for your own actions when you use the podcast and any materials linked to it. This podcast does not constitute professional medical advice, diagnosis or treatment. It is important that users seek medical advice immediately for any medical conditions they might have.

Title Card Photo Credit to Mike Blabac – M

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